close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMG49054.1N-6 DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)    
Predicted Functional Partners:
AMG49052.1
DEAD/DEAH box helicase; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
 
 0.999
AMG49053.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.997
AL523_07595
DNA methyltransferase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.989
AMG49646.1
DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.820
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
   
 
 0.677
AMG48562.1
Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.596
AMG50518.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
  
 0.595
AMG49299.1
Flagellar biosynthesis protein FlaG; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.572
AMG49055.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.556
AMG50702.1
Fibronectin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.545
Your Current Organism:
Enterococcus gallinarum
NCBI taxonomy Id: 1353
Other names: ATCC 49573, CCUG 18658, CECT 970, CIP 103013, DSM 24841, E. gallinarum, JCM 8728, LMG 13129, LMG:13129, NBRC 100675, NCDO 2313, NCIMB 702313, NCTC 12359, Streptococcus gallinarum, strain F87/276, strain PB21
Server load: low (28%) [HD]