| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMG49513.1 | AMG49644.1 | AL523_06885 | AL523_07585 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.465 |
| AMG49572.1 | AMG49644.1 | AL523_07210 | AL523_07585 | DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.429 |
| AMG49572.1 | gyrB | AL523_07210 | AL523_05065 | DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase IV subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.408 |
| AMG49572.1 | gyrB-2 | AL523_07210 | AL523_11005 | DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily. | 0.408 |
| AMG49572.1 | polA | AL523_07210 | AL523_14160 | DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.922 |
| AMG49572.1 | topA | AL523_07210 | AL523_10955 | DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.577 |
| AMG49643.1 | AMG49644.1 | AL523_07580 | AL523_07585 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.598 |
| AMG49644.1 | AMG49513.1 | AL523_07585 | AL523_06885 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.465 |
| AMG49644.1 | AMG49572.1 | AL523_07585 | AL523_07210 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.429 |
| AMG49644.1 | AMG49643.1 | AL523_07585 | AL523_07580 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.598 |
| AMG49644.1 | gyrB | AL523_07585 | AL523_05065 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | DNA topoisomerase IV subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.552 |
| AMG49644.1 | gyrB-2 | AL523_07585 | AL523_11005 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily. | 0.552 |
| AMG49644.1 | polA | AL523_07585 | AL523_14160 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.518 |
| AMG49644.1 | scpA | AL523_07585 | AL523_10195 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.832 |
| AMG49644.1 | topA | AL523_07585 | AL523_10955 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.506 |
| gyrB | AMG49572.1 | AL523_05065 | AL523_07210 | DNA topoisomerase IV subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.408 |
| gyrB | AMG49644.1 | AL523_05065 | AL523_07585 | DNA topoisomerase IV subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.552 |
| gyrB | polA | AL523_05065 | AL523_14160 | DNA topoisomerase IV subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.696 |
| gyrB | topA | AL523_05065 | AL523_10955 | DNA topoisomerase IV subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.408 |
| gyrB-2 | AMG49572.1 | AL523_11005 | AL523_07210 | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily. | DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.408 |
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