STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMG50011.1Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.876
AMG50010.1
3-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.794
AMG50009.1
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.650
AMG50526.1
NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.619
AMG50007.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.616
AMG50008.1
Multidrug ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.609
AMG50022.1
Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.608
AMG48462.1
GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.601
AMG50024.1
NADH-flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.591
AMG49788.1
Tetrahydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family.
    
 0.575
Your Current Organism:
Enterococcus gallinarum
NCBI taxonomy Id: 1353
Other names: ATCC 49573, CCUG 18658, CECT 970, CIP 103013, DSM 24841, E. gallinarum, JCM 8728, LMG 13129, LMG:13129, NBRC 100675, NCDO 2313, NCIMB 702313, NCTC 12359, Streptococcus gallinarum, strain F87/276, strain PB21
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