Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
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[Homology]
Score
AMG50459.1MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)    
Predicted Functional Partners:
AMG50461.1
Urea transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.917
AMG49118.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.732
AMG50460.1
Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily.
 
  
 0.726
AMG49557.1
Metallophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.612
AMG49472.1
Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.584
AMG48461.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.567
AMG50103.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.559
AMG51405.1
Autolysin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.554
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.531
AMG49939.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.496
Your Current Organism:
Enterococcus gallinarum
NCBI taxonomy Id: 1353
Other names: ATCC 49573, CCUG 18658, CECT 970, CIP 103013, DSM 24841, E. gallinarum, JCM 8728, LMG 13129, LMG:13129, NBRC 100675, NCDO 2313, NCIMB 702313, NCTC 12359, Streptococcus gallinarum, strain F87/276, strain PB21
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