STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2ICH0Exonuclease domain-containing protein. (606 aa)    
Predicted Functional Partners:
PAN3
PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]
    
 0.917
A0A1Y2IFF3
Ribonuclease H-like protein.
   
 0.901
A0A1Y2I843
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.876
A0A1Y2ISV0
Ribonuclease H-like protein.
    
0.813
A0A1Y2IR71
Ipi1_N domain-containing protein.
   
 
  0.702
A0A1Y2J0Z9
P-loop containing nucleoside triphosphate hydrolase protein.
  
 
 0.681
A0A1Y2II07
RNB-domain-containing protein; Belongs to the RNR ribonuclease family.
   
 0.665
A0A1Y2J590
Class I glutamine amidotransferase-like protein.
     
 0.650
A0A1Y2I5L7
GMP synthase.
     
 0.648
A0A1Y2I9I1
60S ribosomal protein L7.
   
 0.629
Your Current Organism:
Trametes coccinea
NCBI taxonomy Id: 1353009
Other names: Pycnoporus coccineus BRFM310, T. coccinea BRFM310, Trametes coccinea BRFM310
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