STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2ISM8PWWP domain-containing protein. (439 aa)    
Predicted Functional Partners:
A0A1Y2IQ42
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.833
A0A1Y2IYZ5
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 
 0.821
A0A1Y2ILQ4
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
    
 0.808
A0A1Y2IR29
Methylmalonate-semialdehyde dehydrogenase.
   
 0.803
A0A1Y2IWF1
RNA polymerase II.
    
  0.791
A0A1Y2J1Q3
V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. The active enzyme consists of a catalytic V1 domain attached to an integral membrane V0 proton pore complex. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores; Belongs to the V-ATPase V0D/AC39 subunit family.
    
 0.771
A0A1Y2IZ92
DNA-directed RNA polymerase RPB5 subunit.
    
 0.768
A0A1Y2IF62
Uncharacterized protein.
    
  0.764
A0A1Y2IJE4
Insert subdomain of RNA polymerase alpha subunit.
    
  0.764
A0A1Y2IRA6
RNA polymerase Rpb6.
    
  0.764
Your Current Organism:
Trametes coccinea
NCBI taxonomy Id: 1353009
Other names: Pycnoporus coccineus BRFM310, T. coccinea BRFM310, Trametes coccinea BRFM310
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