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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AND71482.1GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (107 aa)    
Predicted Functional Partners:
rplY
50S ribosomal protein L25/general stress protein Ctc; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
       0.795
AND71481.1
MATE family efflux transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.650
AND71599.1
M protein trans-acting positive regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.624
AND72489.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.563
AND72407.1
VanZ like protein RDD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.530
AND73055.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.526
AND72488.1
Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.496
zapA
Cell division protein ZapA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.493
AND73494.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.490
AND73059.1
NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.452
Your Current Organism:
Enterococcus hirae
NCBI taxonomy Id: 1354
Other names: ATCC 8043, ATCC 9790, CCM 2423, CCUG 18659, CCUG 19917, CFBP 4250, CIP 53.48, DSM 20160, E. hirae, HAMBI 644, IFO 3181, JCM 8729, LMG 6399, LMG:6399, NBRC 3181, NCCB 46070, NCCB 58005, NCIMB 6459, NCTC 12367, strain E.E. Snell strain R
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