STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AND71634.1GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)    
Predicted Functional Partners:
AND71635.1
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.821
nadK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
     0.747
AND71636.1
GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.737
mecA
Adaptor protein MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
  
  
 0.701
AND71638.1
RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
     
 0.633
spxA
Transcriptional regulator Spx; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
  
 
 
 0.612
AND72154.1
Protein RibT; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.610
AND71592.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family.
  
 
 
 0.583
zapA
Cell division protein ZapA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.559
AND72911.1
NADPH-dependent FMN reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.535
Your Current Organism:
Enterococcus hirae
NCBI taxonomy Id: 1354
Other names: ATCC 8043, ATCC 9790, CCM 2423, CCUG 18659, CCUG 19917, CFBP 4250, CIP 53.48, DSM 20160, E. hirae, HAMBI 644, IFO 3181, JCM 8729, LMG 6399, LMG:6399, NBRC 3181, NCCB 46070, NCCB 58005, NCIMB 6459, NCTC 12367, strain E.E. Snell strain R
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.