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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AND71700.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)    
Predicted Functional Partners:
AND71701.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.991
AND71699.1
PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.940
AND71702.1
Metallohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.929
AND71698.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.910
AND72021.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.757
AND73642.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.725
AND72925.1
Prevent-host-death protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.715
AND72937.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.711
mprF-2
Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
  
   
 0.705
AND73169.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.691
Your Current Organism:
Enterococcus hirae
NCBI taxonomy Id: 1354
Other names: ATCC 8043, ATCC 9790, CCM 2423, CCUG 18659, CCUG 19917, CFBP 4250, CIP 53.48, DSM 20160, E. hirae, HAMBI 644, IFO 3181, JCM 8729, LMG 6399, LMG:6399, NBRC 3181, NCCB 46070, NCCB 58005, NCIMB 6459, NCTC 12367, strain E.E. Snell strain R
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.