Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
murQN-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (298 aa)    
Predicted Functional Partners:
AND72249.1
N-acetylglucosamine-6-phosphate deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.990
AND71362.1
PTS N-acetylglucosamine transporter subunit IIABC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.972
AND71852.1
PTS beta-glucoside transporter subunit EIIBCA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.968
AND71850.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.961
nanE
N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
    
  0.907
AND72081.1
Sialic acid utilization regulator, RpiR family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.856
AND71725.1
Serine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.799
AND71556.1
PTS glucose/maltose transporter subunit IIBCA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.732
AND72168.1
PTS beta-glucoside transporter subunit EIIBCA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.732
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
     
 0.524
Your Current Organism:
Enterococcus hirae
NCBI taxonomy Id: 1354
Other names: ATCC 8043, ATCC 9790, CCM 2423, CCUG 18659, CCUG 19917, CFBP 4250, CIP 53.48, DSM 20160, E. hirae, HAMBI 644, IFO 3181, JCM 8729, LMG 6399, LMG:6399, NBRC 3181, NCCB 46070, NCCB 58005, NCIMB 6459, NCTC 12367, strain E.E. Snell strain R
Server load: low (16%) [HD]