STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
AND71908.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)    
Predicted Functional Partners:
AND71909.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
AND73297.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.927
AND71799.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.728
AND72468.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.651
AND73084.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.651
AND71575.1
Permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.650
dltA
D-alanine--poly(phosphoribitol) ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-de [...]
 
  
 0.569
AND71912.1
D-alanyl-lipoteichoic acid biosynthesis protein DltB; Could be involved in the transport of activated D-alanine through the membrane.
 
     0.550
AND73298.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.547
dltC
D-alanine--poly(phosphoribitol) ligase subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
 
    0.505
Your Current Organism:
Enterococcus hirae
NCBI taxonomy Id: 1354
Other names: ATCC 8043, ATCC 9790, CCM 2423, CCUG 18659, CCUG 19917, CFBP 4250, CIP 53.48, DSM 20160, E. hirae, HAMBI 644, IFO 3181, JCM 8729, LMG 6399, LMG:6399, NBRC 3181, NCCB 46070, NCCB 58005, NCIMB 6459, NCTC 12367, strain E.E. Snell strain R
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