Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AND72019.1Iron-sulfur cluster biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (97 aa)    
Predicted Functional Partners:
AND72018.1
Potassium transporter Trk; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.902
AND72016.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.801
AND72017.1
Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.801
AND73683.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.801
AND73056.1
Lipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.778
AND73029.1
Carboxylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.764
greA
Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
     
 0.606
AND72180.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.595
mecA
Adaptor protein MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
  
   
 0.536
AND72020.1
Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.524
Your Current Organism:
Enterococcus hirae
NCBI taxonomy Id: 1354
Other names: ATCC 8043, ATCC 9790, CCM 2423, CCUG 18659, CCUG 19917, CFBP 4250, CIP 53.48, DSM 20160, E. hirae, HAMBI 644, IFO 3181, JCM 8729, LMG 6399, LMG:6399, NBRC 3181, NCCB 46070, NCCB 58005, NCIMB 6459, NCTC 12367, strain E.E. Snell strain R
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