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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AND72102.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)    
Predicted Functional Partners:
AND71545.1
With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     0.853
AND72103.1
PTS sorbitol transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.851
AND72104.1
PTS sorbitol transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.838
AND72106.1
NAD(P)-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.829
AND72107.1
PTS sorbitol transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.811
AND73055.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.652
AND73056.1
Lipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.651
rpoE
DNA-directed RNA polymerase subunit delta; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family.
       0.602
AND72105.1
Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.561
AND73687.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
    0.484
Your Current Organism:
Enterococcus hirae
NCBI taxonomy Id: 1354
Other names: ATCC 8043, ATCC 9790, CCM 2423, CCUG 18659, CCUG 19917, CFBP 4250, CIP 53.48, DSM 20160, E. hirae, HAMBI 644, IFO 3181, JCM 8729, LMG 6399, LMG:6399, NBRC 3181, NCCB 46070, NCCB 58005, NCIMB 6459, NCTC 12367, strain E.E. Snell strain R
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