| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AND71557.1 | mprF | A6P53_01295 | A6P53_04505 | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.526 |
| AND71557.1 | mprF-3 | A6P53_01295 | A6P53_12220 | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.526 |
| AND72039.1 | mprF | A6P53_03850 | A6P53_04505 | AI-2E family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.463 |
| AND72039.1 | mprF-3 | A6P53_03850 | A6P53_12220 | AI-2E family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.469 |
| AND72144.1 | AND72145.1 | A6P53_04510 | A6P53_04515 | Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transglycosylase SLT domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.569 |
| AND72144.1 | AND72146.1 | A6P53_04510 | A6P53_04520 | Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DUF368 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.433 |
| AND72144.1 | mprF | A6P53_04510 | A6P53_04505 | Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.761 |
| AND72145.1 | AND72144.1 | A6P53_04515 | A6P53_04510 | Transglycosylase SLT domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.569 |
| AND72145.1 | AND72146.1 | A6P53_04515 | A6P53_04520 | Transglycosylase SLT domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DUF368 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.666 |
| AND72145.1 | mprF | A6P53_04515 | A6P53_04505 | Transglycosylase SLT domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.540 |
| AND72146.1 | AND72144.1 | A6P53_04520 | A6P53_04510 | DUF368 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.433 |
| AND72146.1 | AND72145.1 | A6P53_04520 | A6P53_04515 | DUF368 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transglycosylase SLT domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.666 |
| AND72146.1 | mprF | A6P53_04520 | A6P53_04505 | DUF368 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.431 |
| AND72529.1 | mprF | A6P53_06525 | A6P53_04505 | AI-2E family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.437 |
| AND72529.1 | mprF-3 | A6P53_06525 | A6P53_12220 | AI-2E family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.432 |
| dltA | mprF | A6P53_03185 | A6P53_04505 | D-alanine--poly(phosphoribitol) ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-de [...] | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.403 |
| dltA | mprF-3 | A6P53_03185 | A6P53_12220 | D-alanine--poly(phosphoribitol) ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-de [...] | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.474 |
| mprF | AND71557.1 | A6P53_04505 | A6P53_01295 | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.526 |
| mprF | AND72039.1 | A6P53_04505 | A6P53_03850 | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | AI-2E family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.463 |
| mprF | AND72144.1 | A6P53_04505 | A6P53_04510 | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.761 |
