STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AND72182.1Sodium:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (694 aa)    
Predicted Functional Partners:
AND72181.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.893
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
 0.667
AND72185.1
Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.652
AND72342.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.652
AND72665.1
ClC family H(+)/Cl(-) exchange transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.522
truB
tRNA pseudouridine(55) synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
       0.457
AND72180.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.443
AND72150.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
   0.430
napA
Sodium:proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Can also transport lithium.
   
 
 0.414
AND72677.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.407
Your Current Organism:
Enterococcus hirae
NCBI taxonomy Id: 1354
Other names: ATCC 8043, ATCC 9790, CCM 2423, CCUG 18659, CCUG 19917, CFBP 4250, CIP 53.48, DSM 20160, E. hirae, HAMBI 644, IFO 3181, JCM 8729, LMG 6399, LMG:6399, NBRC 3181, NCCB 46070, NCCB 58005, NCIMB 6459, NCTC 12367, strain E.E. Snell strain R
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.