| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AND72487.1 | apt | A6P53_06310 | A6P53_05765 | Guanylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.951 |
| AND72487.1 | gmk | A6P53_06310 | A6P53_12150 | Guanylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.926 |
| AND72487.1 | guaA | A6P53_06310 | A6P53_00130 | Guanylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.958 |
| AND72487.1 | guaB | A6P53_06310 | A6P53_12805 | Guanylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.483 |
| AND72487.1 | guaC | A6P53_06310 | A6P53_05245 | Guanylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.913 |
| AND72487.1 | hpt | A6P53_06310 | A6P53_12020 | Guanylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.934 |
| AND72487.1 | xpt | A6P53_06310 | A6P53_05150 | Guanylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.954 |
| apt | AND72487.1 | A6P53_05765 | A6P53_06310 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.951 |
| apt | gmk | A6P53_05765 | A6P53_12150 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.951 |
| apt | guaA | A6P53_05765 | A6P53_00130 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.981 |
| apt | guaB | A6P53_05765 | A6P53_12805 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.524 |
| apt | guaC | A6P53_05765 | A6P53_05245 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.930 |
| apt | hpt | A6P53_05765 | A6P53_12020 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.934 |
| apt | purA | A6P53_05765 | A6P53_00075 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.586 |
| apt | purH | A6P53_05765 | A6P53_05225 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.960 |
| apt | purM | A6P53_05765 | A6P53_05215 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.528 |
| apt | xpt | A6P53_05765 | A6P53_05150 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.927 |
| gmk | AND72487.1 | A6P53_12150 | A6P53_06310 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Guanylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.926 |
| gmk | apt | A6P53_12150 | A6P53_05765 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.951 |
| gmk | guaA | A6P53_12150 | A6P53_00130 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.964 |
STRING v12.5 is now available!
