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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AND72313.1comEA protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)    
Predicted Functional Partners:
AND72315.1
DNA internalization-related competence protein ComEC/Rec2; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.958
AND72314.1
Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.929
HolA
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.857
AND73009.1
DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.758
AND73360.1
Secretion system protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.750
AND73361.1
Secretion system protein E; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.743
AND72626.1
Phosphoglycolate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.682
AND73607.1
Peptidase A24; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.665
AND73359.1
Competence protein ComG; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.644
ssb
Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
  
 0.641
Your Current Organism:
Enterococcus hirae
NCBI taxonomy Id: 1354
Other names: ATCC 8043, ATCC 9790, CCM 2423, CCUG 18659, CCUG 19917, CFBP 4250, CIP 53.48, DSM 20160, E. hirae, HAMBI 644, IFO 3181, JCM 8729, LMG 6399, LMG:6399, NBRC 3181, NCCB 46070, NCCB 58005, NCIMB 6459, NCTC 12367, strain E.E. Snell strain R
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.