Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AND72348.1HxlR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa)    
Predicted Functional Partners:
addA
Helicase-exonuclease AddAB subunit AddA; ATP-dependent DNA helicase.
     
 0.814
rexB
ATP-dependent helicase; ATP-dependent DNA helicase; Belongs to the helicase family. AddB/RexB type 2 subfamily.
       0.813
pheS
phenylalanine--tRNA ligase subunit alpha; Catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
       0.673
AND72944.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.608
pheT
phenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
       0.599
AND71496.1
PemK family transcriptional regulator; Toxic component of a type II toxin-antitoxin (TA) system.
   
    0.490
AND71665.1
PemK family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.490
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
   
    0.475
AND71468.1
NAD-dependent protein deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.450
AND73354.1
Adenine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.409
Your Current Organism:
Enterococcus hirae
NCBI taxonomy Id: 1354
Other names: ATCC 8043, ATCC 9790, CCM 2423, CCUG 18659, CCUG 19917, CFBP 4250, CIP 53.48, DSM 20160, E. hirae, HAMBI 644, IFO 3181, JCM 8729, LMG 6399, LMG:6399, NBRC 3181, NCCB 46070, NCCB 58005, NCIMB 6459, NCTC 12367, strain E.E. Snell strain R
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