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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AND72450.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)    
Predicted Functional Partners:
AND72449.1
DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.748
AND72448.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.572
AND72445.1
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.512
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
     
 0.429
AND72028.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.412
AND72029.1
Glutamate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.412
AND72032.1
Chitinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.412
AND72447.1
Cro/Cl family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.412
AND72543.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.412
AND72031.1
Sensory protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.405
Your Current Organism:
Enterococcus hirae
NCBI taxonomy Id: 1354
Other names: ATCC 8043, ATCC 9790, CCM 2423, CCUG 18659, CCUG 19917, CFBP 4250, CIP 53.48, DSM 20160, E. hirae, HAMBI 644, IFO 3181, JCM 8729, LMG 6399, LMG:6399, NBRC 3181, NCCB 46070, NCCB 58005, NCIMB 6459, NCTC 12367, strain E.E. Snell strain R
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