Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AND72677.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)    
Predicted Functional Partners:
AND72678.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.796
AND72679.1
Signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.796
AND72680.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.793
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
       0.784
AND71439.1
M protein trans-acting positive regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.673
AND71999.1
Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.668
AND72544.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.645
AND71988.1
Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.642
AND72785.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.642
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
   
 0.636
Your Current Organism:
Enterococcus hirae
NCBI taxonomy Id: 1354
Other names: ATCC 8043, ATCC 9790, CCM 2423, CCUG 18659, CCUG 19917, CFBP 4250, CIP 53.48, DSM 20160, E. hirae, HAMBI 644, IFO 3181, JCM 8729, LMG 6399, LMG:6399, NBRC 3181, NCCB 46070, NCCB 58005, NCIMB 6459, NCTC 12367, strain E.E. Snell strain R
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