Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CopYPenicillinase repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)    
Predicted Functional Partners:
copZ
Copper-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.984
CopB
Copper-translocating P-type ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.896
CopA
ATPase P; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.836
AND72933.1
Cadmium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.753
AND72925.1
Prevent-host-death protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.603
AND72931.1
Topology modulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.575
cutC
Copper homeostasis protein CutC; Participates in the control of copper homeostasis. Belongs to the CutC family.
      
 0.562
groS
Co-chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
   
    0.476
grpE
Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...]
   
    0.476
AND72980.1
Divalent metal cation transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.456
Your Current Organism:
Enterococcus hirae
NCBI taxonomy Id: 1354
Other names: ATCC 8043, ATCC 9790, CCM 2423, CCUG 18659, CCUG 19917, CFBP 4250, CIP 53.48, DSM 20160, E. hirae, HAMBI 644, IFO 3181, JCM 8729, LMG 6399, LMG:6399, NBRC 3181, NCCB 46070, NCCB 58005, NCIMB 6459, NCTC 12367, strain E.E. Snell strain R
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