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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AND73326.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)    
Predicted Functional Partners:
mecA
Adaptor protein MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
 
   
 0.866
AND73325.1
Oligoendopeptidase F; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.818
spxA
Transcriptional regulator Spx; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
     
 0.771
AND73354.1
Adenine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.749
AND72175.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.647
AND72091.1
Nucleic acid-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.637
AND72313.1
comEA protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.595
AND71705.1
CAAX protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.573
ezrA
Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
     0.560
AND73607.1
Peptidase A24; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.554
Your Current Organism:
Enterococcus hirae
NCBI taxonomy Id: 1354
Other names: ATCC 8043, ATCC 9790, CCM 2423, CCUG 18659, CCUG 19917, CFBP 4250, CIP 53.48, DSM 20160, E. hirae, HAMBI 644, IFO 3181, JCM 8729, LMG 6399, LMG:6399, NBRC 3181, NCCB 46070, NCCB 58005, NCIMB 6459, NCTC 12367, strain E.E. Snell strain R
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