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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AND73498.1TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)    
Predicted Functional Partners:
AND73497.1
Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.646
AND73496.1
Multidrug ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.640
AND73271.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.553
AND71439.1
M protein trans-acting positive regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.543
AND73574.1
PadR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.532
AND72481.1
Cation transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.478
AND73392.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.472
AND72799.1
Glucosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.470
pth
aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
    0.470
AND73261.1
AAC(6')-Ii family aminoglycoside 6'-N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.457
Your Current Organism:
Enterococcus hirae
NCBI taxonomy Id: 1354
Other names: ATCC 8043, ATCC 9790, CCM 2423, CCUG 18659, CCUG 19917, CFBP 4250, CIP 53.48, DSM 20160, E. hirae, HAMBI 644, IFO 3181, JCM 8729, LMG 6399, LMG:6399, NBRC 3181, NCCB 46070, NCCB 58005, NCIMB 6459, NCTC 12367, strain E.E. Snell strain R
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