| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AND72274.1 | guaA | A6P53_05180 | A6P53_00130 | Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.949 |
| AND72274.1 | prs-2 | A6P53_05180 | A6P53_12185 | Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.717 |
| AND72274.1 | purA | A6P53_05180 | A6P53_00075 | Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.999 |
| AND72274.1 | purH | A6P53_05180 | A6P53_05225 | Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
| AND72274.1 | purR | A6P53_05180 | A6P53_12195 | Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Pur operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.586 |
| AND73542.1 | AND73543.1 | A6P53_12200 | A6P53_12205 | Zinc ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Zinc ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| AND73542.1 | AND73544.1 | A6P53_12200 | A6P53_12210 | Zinc ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Zinc ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family. | 0.998 |
| AND73542.1 | glmU | A6P53_12200 | A6P53_12190 | Zinc ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.693 |
| AND73542.1 | prs-2 | A6P53_12200 | A6P53_12185 | Zinc ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.406 |
| AND73542.1 | purR | A6P53_12200 | A6P53_12195 | Zinc ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pur operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.793 |
| AND73543.1 | AND73542.1 | A6P53_12205 | A6P53_12200 | Zinc ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Zinc ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| AND73543.1 | AND73544.1 | A6P53_12205 | A6P53_12210 | Zinc ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Zinc ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family. | 0.999 |
| AND73543.1 | glmU | A6P53_12205 | A6P53_12190 | Zinc ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.631 |
| AND73543.1 | purR | A6P53_12205 | A6P53_12195 | Zinc ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pur operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.651 |
| AND73544.1 | AND73542.1 | A6P53_12210 | A6P53_12200 | Zinc ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family. | Zinc ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
| AND73544.1 | AND73543.1 | A6P53_12210 | A6P53_12205 | Zinc ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family. | Zinc ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| AND73544.1 | glmU | A6P53_12210 | A6P53_12190 | Zinc ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family. | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.479 |
| AND73544.1 | purR | A6P53_12210 | A6P53_12195 | Zinc ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family. | Pur operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.632 |
| codY | guaA | A6P53_04830 | A6P53_00130 | Transcriptional repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.455 |
| codY | purA | A6P53_04830 | A6P53_00075 | Transcriptional repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.425 |
