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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AND73555.1M16 family metallopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)    
Predicted Functional Partners:
AND73554.1
Zinc protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.991
AND72685.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.896
AND73576.1
NAD(P)-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.873
mscL
Mechanosensitive ion channel protein MscL; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
       0.806
AND73553.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.793
cinA
Competence/damage-inducible protein A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
 
   
 0.781
atpH
F0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
   
 
 0.763
AND73552.1
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.755
atpA
F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
   
 
 0.696
atpC
Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
 0.678
Your Current Organism:
Enterococcus hirae
NCBI taxonomy Id: 1354
Other names: ATCC 8043, ATCC 9790, CCM 2423, CCUG 18659, CCUG 19917, CFBP 4250, CIP 53.48, DSM 20160, E. hirae, HAMBI 644, IFO 3181, JCM 8729, LMG 6399, LMG:6399, NBRC 3181, NCCB 46070, NCCB 58005, NCIMB 6459, NCTC 12367, strain E.E. Snell strain R
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