STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrDHypothetical protein; Catalyzes the conversion of dihydroorotate to orotate. (298 aa)    
Predicted Functional Partners:
EQB89840.1
Hypothetical protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 0.999
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 0.999
pyrK
Hypothetical protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
 
 0.999
EQB87507.1
Anaerobic sulfite reductase subunit B; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 0.997
pyrB
Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 
 0.994
EQB86695.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 0.990
EQB90374.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 0.982
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 0.967
EQB89361.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.961
EQB88487.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 0.958
Your Current Organism:
Clostridium sp. BL8
NCBI taxonomy Id: 1354301
Other names: C. sp. BL8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.