STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
erpAIron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters. (117 aa)    
Predicted Functional Partners:
grxD
Glutaredoxin-4.
   
 0.839
sufU
Zinc-dependent sulfurtransferase SufU.
  
  
 0.830
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
  
 0.773
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
     
 0.758
ygfZ
tRNA-modifying protein YgfZ; Belongs to the GcvT family.
  
 
 0.640
mdtC_1
Multidrug resistance protein MdtC; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.559
ascD_1
CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase.
  
 
 0.550
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 
 0.530
sufD
FeS cluster assembly protein SufD.
  
 
 0.496
sufB
FeS cluster assembly protein SufB.
  
 
 0.494
Your Current Organism:
Ferrovum sp. JA12
NCBI taxonomy Id: 1356299
Other names: F. sp. JA12
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