STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BEH_04535MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)    
Predicted Functional Partners:
BEH_02160
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.804
icmF
methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
    
 0.700
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.696
BEH_17285
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.682
BEH_19410
methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.666
BEH_04530
Tautomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.511
BEH_11510
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.506
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.493
BEH_05665
Malonate decarboxylase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.437
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.435
Your Current Organism:
Bacillus endophyticus
NCBI taxonomy Id: 135735
Other names: Bacillus endophyticus Reva et al. 2002, CIP 106778, DSM 13796, JCM 12211, UCM B-5715, strain 2DT
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