STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnhAAn endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)    
Predicted Functional Partners:
BEH_15725
5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.873
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 0.873
BEH_05935
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.860
rnhB
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
   
 
 0.780
BEH_15900
DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.711
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.711
BEH_23300
Single-stranded DNA-binding protein; Binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.708
BEH_24045
Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
   
 
 0.708
BEH_00265
DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.647
BEH_20000
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
  
  
 0.630
Your Current Organism:
Bacillus endophyticus
NCBI taxonomy Id: 135735
Other names: Bacillus endophyticus Reva et al. 2002, CIP 106778, DSM 13796, JCM 12211, UCM B-5715, strain 2DT
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