STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iolA-2Methylmalonate-semialdehyde dehydrogenase; Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively. (485 aa)    
Predicted Functional Partners:
BEH_09605
5-deoxyglucuronate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.899
iolD
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Involved in the cleavage of the C1-C2 bond of 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy-glucuronate (5DG).
 
  
 0.888
iolC
5-dehydro-2-deoxygluconokinase; Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2- deoxy-D-gluconate (DKGP).
 
    0.848
iolE
Inosose dehydratase; Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).
  
 
 0.828
BEH_10700
Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.806
BEH_08055
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.804
BEH_16975
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.799
BEH_21175
Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.788
BEH_16450
PTS beta-glucoside transporter subunit IIABC; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.758
BEH_22270
Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.715
Your Current Organism:
Bacillus endophyticus
NCBI taxonomy Id: 135735
Other names: Bacillus endophyticus Reva et al. 2002, CIP 106778, DSM 13796, JCM 12211, UCM B-5715, strain 2DT
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