BSLG_07940 protein (Batrachochytrium salamandrivorans)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

BSLG_07940

Uncharacterized protein. (368 aa)

Predicted Functional Partners:

BSLG_02848

0.789

BSLG_03958

0.729

BSLG_03144

0.729

BSLG_00068

0.718

BSLG_02174

0.700

BSLG_00911

0.676

BSLG_00240

0.676

BSLG_09819

0.631

BSLG_08892

0.631

BSLG_02372

0.536

Your Current Organism:

Batrachochytrium salamandrivorans

NCBI taxonomy Id: 1357716
Other names: AMFP13/1, B. salamandrivorans, Batrachochytrium salamandrivorans Martel, Blooi, Bossuyt & Pasmans 2013, CBS 135744, Chytridiales sp. AM-2013, Chytridiomycota sp. AM-2013

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BSLG_00068	BSLG_02174	A0A1S8WA20	A0A1S8W251	Uncharacterized protein.	Isovaleryl-CoA dehydrogenase, mitochondrial.	0.794
BSLG_00068	BSLG_07940	A0A1S8WA20	A0A1S8VHR3	Uncharacterized protein.	Uncharacterized protein.	0.718
BSLG_00240	BSLG_00911	A0A1S8W9I6	A0A1S8W746	STAS domain-containing protein.	Uncharacterized protein.	0.876
BSLG_00240	BSLG_03144	A0A1S8W9I6	A0A1S8VYV0	STAS domain-containing protein.	Uncharacterized protein.	0.401
BSLG_00240	BSLG_03958	A0A1S8W9I6	A0A1S8VW28	STAS domain-containing protein.	Alpha-carbonic anhydrase domain-containing protein.	0.401
BSLG_00240	BSLG_07940	A0A1S8W9I6	A0A1S8VHR3	STAS domain-containing protein.	Uncharacterized protein.	0.676
BSLG_00911	BSLG_00240	A0A1S8W746	A0A1S8W9I6	Uncharacterized protein.	STAS domain-containing protein.	0.876
BSLG_00911	BSLG_07940	A0A1S8W746	A0A1S8VHR3	Uncharacterized protein.	Uncharacterized protein.	0.676
BSLG_02174	BSLG_00068	A0A1S8W251	A0A1S8WA20	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.794
BSLG_02174	BSLG_02848	A0A1S8W251	A0A1S8W160	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.535
BSLG_02174	BSLG_07940	A0A1S8W251	A0A1S8VHR3	Isovaleryl-CoA dehydrogenase, mitochondrial.	Uncharacterized protein.	0.700
BSLG_02372	BSLG_07940	A0A1S8W1A1	A0A1S8VHR3	Adenine phosphoribosyltransferase.	Uncharacterized protein.	0.536
BSLG_02848	BSLG_02174	A0A1S8W160	A0A1S8W251	Uncharacterized protein.	Isovaleryl-CoA dehydrogenase, mitochondrial.	0.535
BSLG_02848	BSLG_07940	A0A1S8W160	A0A1S8VHR3	Uncharacterized protein.	Uncharacterized protein.	0.789
BSLG_03144	BSLG_00240	A0A1S8VYV0	A0A1S8W9I6	Uncharacterized protein.	STAS domain-containing protein.	0.401
BSLG_03144	BSLG_07940	A0A1S8VYV0	A0A1S8VHR3	Uncharacterized protein.	Uncharacterized protein.	0.729
BSLG_03958	BSLG_00240	A0A1S8VW28	A0A1S8W9I6	Alpha-carbonic anhydrase domain-containing protein.	STAS domain-containing protein.	0.401
BSLG_03958	BSLG_07940	A0A1S8VW28	A0A1S8VHR3	Alpha-carbonic anhydrase domain-containing protein.	Uncharacterized protein.	0.729
BSLG_07940	BSLG_00068	A0A1S8VHR3	A0A1S8WA20	Uncharacterized protein.	Uncharacterized protein.	0.718
BSLG_07940	BSLG_00240	A0A1S8VHR3	A0A1S8W9I6	Uncharacterized protein.	STAS domain-containing protein.	0.676

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

13

average node degree:

2.36

avg. local clustering coefficient:

0.855

expected number of edges:

11

PPI enrichment p-value:

0.263

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006352

DNA-templated transcription, initiation

5 of 25

1.83

2.2

1.35e-05

GO:0006281

DNA repair

4 of 60

1.35

1.15

0.0011

GO:0034654

Nucleobase-containing compound biosynthetic process

6 of 152

1.13

1.07

0.00024

GO:0090304

Nucleic acid metabolic process

9 of 316

0.98

1.02

1.35e-05

GO:0009059

Macromolecule biosynthetic process

6 of 256

0.9

0.73

0.0015

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016987

Sigma factor activity

5 of 25

1.83

2.3

7.03e-06

GO:0003700

DNA-binding transcription factor activity

6 of 75

1.43

1.72

1.22e-05

GO:0003677

DNA binding

7 of 267

0.95

0.84

0.00045

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5222

Oxoglutarate/iron-dependent dioxygenase, and methylated-DNA-[protein]-cysteine S-methyltransferase activity

3 of 5

2.31

1.63

0.00086

CL:5180

Mixed, incl. LysR, substrate-binding, and Pirin

4 of 35

1.59

1.29

0.0013

CL:2233

Mixed, incl. Sigma-70 factor, region 1.2, and Smr domain

2 of 6

2.05

0.78

0.0357

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0000428

DNA-directed RNA polymerase complex

5 of 47

1.56

1.72

5.40e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0731

Sigma factor

4 of 23

1.77

1.88

7.09e-05

KW-0238

DNA-binding

7 of 150

1.2

1.36

1.20e-05

KW-0805

Transcription regulation

5 of 104

1.21

1.1

0.00053

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF04545

Sigma-70, region 4

5 of 10

2.23

3.41

1.19e-07

PF00140

Sigma-70 factor, region 1.2

3 of 3

2.53

2.15

9.92e-05

PF04542

Sigma-70 region 2

4 of 20

1.83

1.87

9.92e-05

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR007630

RNA polymerase sigma-70 region 4

5 of 6

2.45

3.76

4.83e-08

IPR000943

RNA polymerase sigma-70

5 of 6

2.45

3.76

4.83e-08

IPR014284

RNA polymerase sigma-70 like domain

5 of 22

1.89

2.51

2.75e-06

IPR013324

RNA polymerase sigma factor, region 3/4-like

5 of 22

1.89

2.51

2.75e-06

IPR009042

RNA polymerase sigma-70 region 1.2

3 of 3

2.53

2.15

0.00010

(more ...)

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