BSLG_05870 protein (Batrachochytrium salamandrivorans)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

BSLG_05870

Uncharacterized protein. (227 aa)

Predicted Functional Partners:

BSLG_06820

0.965

BSLG_00500

0.962

BSLG_08172

0.954

BSLG_04281

0.954

BSLG_01146

0.954

BSLG_09270

0.861

BSLG_02826

0.861

BSLG_01168

0.861

BSLG_00117

0.847

BSLG_01217

0.838

Your Current Organism:

Batrachochytrium salamandrivorans

NCBI taxonomy Id: 1357716
Other names: AMFP13/1, B. salamandrivorans, Batrachochytrium salamandrivorans Martel, Blooi, Bossuyt & Pasmans 2013, CBS 135744, Chytridiales sp. AM-2013, Chytridiomycota sp. AM-2013

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BSLG_00117	BSLG_05870	A0A1S8W9X5	A0A1S8VP29	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	Uncharacterized protein.	0.847
BSLG_00500	BSLG_01146	A0A1S8W8J2	A0A1S8W627	Uncharacterized protein.	Uncharacterized protein.	0.753
BSLG_00500	BSLG_04281	A0A1S8W8J2	A0A1S8VVA0	Uncharacterized protein.	Flavin_Reduct domain-containing protein.	0.753
BSLG_00500	BSLG_05870	A0A1S8W8J2	A0A1S8VP29	Uncharacterized protein.	Uncharacterized protein.	0.962
BSLG_00500	BSLG_06820	A0A1S8W8J2	A0A1S8VKC4	Uncharacterized protein.	CHORD domain-containing protein.	0.959
BSLG_00500	BSLG_08172	A0A1S8W8J2	A0A1S8VFZ0	Uncharacterized protein.	Heat shock protein HSP 90-beta.	0.768
BSLG_01146	BSLG_00500	A0A1S8W627	A0A1S8W8J2	Uncharacterized protein.	Uncharacterized protein.	0.753
BSLG_01146	BSLG_01217	A0A1S8W627	A0A1S8W5Q9	Uncharacterized protein.	Uncharacterized protein.	0.720
BSLG_01146	BSLG_05870	A0A1S8W627	A0A1S8VP29	Uncharacterized protein.	Uncharacterized protein.	0.954
BSLG_01146	BSLG_06820	A0A1S8W627	A0A1S8VKC4	Uncharacterized protein.	CHORD domain-containing protein.	0.949
BSLG_01168	BSLG_05870	A0A1S8W600	A0A1S8VP29	Uncharacterized protein; Belongs to the SKP1 family.	Uncharacterized protein.	0.861
BSLG_01217	BSLG_01146	A0A1S8W5Q9	A0A1S8W627	Uncharacterized protein.	Uncharacterized protein.	0.720
BSLG_01217	BSLG_04281	A0A1S8W5Q9	A0A1S8VVA0	Uncharacterized protein.	Flavin_Reduct domain-containing protein.	0.720
BSLG_01217	BSLG_05870	A0A1S8W5Q9	A0A1S8VP29	Uncharacterized protein.	Uncharacterized protein.	0.838
BSLG_01217	BSLG_08172	A0A1S8W5Q9	A0A1S8VFZ0	Uncharacterized protein.	Heat shock protein HSP 90-beta.	0.720
BSLG_02826	BSLG_05870	A0A1S8VZL9	A0A1S8VP29	Uncharacterized protein; Belongs to the SKP1 family.	Uncharacterized protein.	0.861
BSLG_04281	BSLG_00500	A0A1S8VVA0	A0A1S8W8J2	Flavin_Reduct domain-containing protein.	Uncharacterized protein.	0.753
BSLG_04281	BSLG_01217	A0A1S8VVA0	A0A1S8W5Q9	Flavin_Reduct domain-containing protein.	Uncharacterized protein.	0.720
BSLG_04281	BSLG_05870	A0A1S8VVA0	A0A1S8VP29	Flavin_Reduct domain-containing protein.	Uncharacterized protein.	0.954
BSLG_04281	BSLG_06820	A0A1S8VVA0	A0A1S8VKC4	Flavin_Reduct domain-containing protein.	CHORD domain-containing protein.	0.949

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

17

average node degree:

3.09

avg. local clustering coefficient:

0.855

expected number of edges:

14

PPI enrichment p-value:

0.237

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019303

D-ribose catabolic process

2 of 2

2.95

1.07

0.0115

GO:0046365

Monosaccharide catabolic process

3 of 44

1.79

0.98

0.0116

GO:0005996

Monosaccharide metabolic process

4 of 116

1.49

0.9

0.0115

GO:0005975

Carbohydrate metabolic process

6 of 416

1.11

0.76

0.0082

GO:0016052

Carbohydrate catabolic process

4 of 225

1.2

0.58

0.0489

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004747

Ribokinase activity

2 of 2

2.95

1.09

0.0106

GO:0004348

Glucosylceramidase activity

2 of 2

2.95

1.09

0.0106

GO:0004034

Aldose 1-epimerase activity

2 of 2

2.95

1.09

0.0106

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:11819

Carbohydrate metabolic process, and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

6 of 153

1.55

1.89

1.16e-05

CL:14166

Glycosaminoglycan degradation, and Alpha galactosidase A

3 of 38

1.85

1.12

0.0060

CL:11935

Ribose-phosphate pyrophosphokinase, and Ribokinase

2 of 6

2.47

1.1

0.0097

CL:14172

Mixed, incl. Glucosylceramidase activity, and Glycosyl hydrolases family 35

2 of 8

2.35

1.08

0.0103

CL:12003

Starch and sucrose metabolism, and Galactose catabolism

3 of 54

1.7

0.99

0.0097

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00511

Other glycan degradation

3 of 22

2.09

1.9

0.00018

map00600

Sphingolipid metabolism

3 of 42

1.81

1.51

0.00073

map00052

Galactose metabolism

3 of 50

1.73

1.43

0.00090

map00030

Pentose phosphate pathway

2 of 35

1.71

0.83

0.0226

map01100

Metabolic pathways

11 of 2756

0.55

0.47

0.00013

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-71387

Metabolism of carbohydrates

7 of 263

1.38

1.75

2.99e-06

MAP-71336

Pentose phosphate pathway

3 of 26

2.01

1.51

0.0011

MAP-1660662

Glycosphingolipid metabolism

3 of 39

1.84

1.28

0.0027

MAP-70370

Galactose catabolism

2 of 8

2.35

1.1

0.0094

MAP-428157

Sphingolipid metabolism

3 of 99

1.43

0.74

0.0258

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0119

Carbohydrate metabolism

3 of 21

2.11

1.7

0.00050

KW-0630

Potassium

2 of 6

2.47

1.32

0.0038

KW-0418

Kinase

4 of 201

1.25

0.92

0.0043

KW-0808

Transferase

5 of 721

0.79

0.45

0.0408

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00294

pfkB family carbohydrate kinase

4 of 7

2.71

3.52

2.64e-07

PF17189

Glycosyl hydrolase family 30 beta sandwich domain

2 of 2

2.95

1.38

0.0032

PF02055

Glycosyl hydrolase family 30 TIM-barrel domain

2 of 2

2.95

1.38

0.0032

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR011611

Carbohydrate kinase PfkB

4 of 6

2.78

3.4

4.88e-07

IPR029056

Ribokinase-like

4 of 10

2.55

3.14

1.16e-06

IPR033452

Glycosyl hydrolase family 30, beta sandwich domain

2 of 2

2.95

1.22

0.0063

IPR011877

Ribokinase

2 of 2

2.95

1.22

0.0063

IPR002139

Ribokinase/fructokinase

2 of 2

2.95

1.22

0.0063

(more ...)

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