STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)    
Predicted Functional Partners:
KIL53244.1
Pfam: Pyruvate kinase, alpha/beta domain; Pfam: Pyruvate kinase, barrel domain; Pfam: PEP-utilising enzyme, mobile domain; TIGRFAM: pyruv_kin: pyruvate kinase; PRINTS: Pyruvate kinase family signature; Belongs to the pyruvate kinase family.
 
 
 0.999
pgi
PRINTS: Glucose-6-phosphate isomerase signature; Pfam: Phosphoglucose isomerase; Belongs to the GPI family.
  
 0.988
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
  
 0.976
KIL44011.1
Pfam: Fructose-bisphosphate aldolase class-II; TIGRFAM: cbbA: ketose-bisphosphate aldolase; TIGRFAM: fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II.
 
 
 0.973
fda
Pfam: Fructose-bisphosphate aldolase class-I.
  
 0.960
KIL44052.1
Hypothetical protein; Overlaps another CDS; TIGRFAM: 1-PFK: hexose kinase, 1-phosphofructokinase family; TIGRFAM: pfkB: 1-phosphofructokinase; Pfam: pfkB family carbohydrate kinase.
  
  
 0.921
mtlD
Mannitol-1-phosphate 5-dehydrogenase; Overlaps another CDS; Pfam: Mannitol dehydrogenase Rossmann domain; Pfam: Mannitol dehydrogenase C-terminal domain; PRINTS: Mannitol dehydrogenase signature.
 
  
 0.918
KIL50574.1
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.917
KIL44074.1
Fructokinase; Pfam: pfkB family carbohydrate kinase; PRINTS: Ribokinase signature; Belongs to the carbohydrate kinase PfkB family.
  
 
 0.910
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.909
Your Current Organism:
Jeotgalibacillus alimentarius
NCBI taxonomy Id: 135826
Other names: Bacillus kangii, J. alimentarius, JCM 10872, Jeotgalibacillus alimentarius Yoon et al. 2001, KCCM 80002, strain YKJ-13
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