STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL2RBFibronectin type-III domain-containing protein. (562 aa)    
Predicted Functional Partners:
JAK1
Protein kinase domain-containing protein.
     
  0.951
IL2RG
Fibronectin type-III domain-containing protein.
     
  0.934
IL15
Interleukin; Belongs to the IL-15/IL-21 family.
     
  0.910
LOC100011470
Signal transducer and activator of transcription.
     
  0.906
LOC100012174
Signal transducer and activator of transcription.
     
  0.906
IL2
Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.
     
  0.900
RHOA
Uncharacterized protein.
     
  0.900
JAK2
Tyrosine-protein kinase.
     
  0.850
IL15RA
Sushi domain-containing protein.
     
  0.821
TYK2
Tyrosine-protein kinase.
     
  0.767
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.