STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NFX1Nuclear transcription factor, X-box binding 1. (1120 aa)    
Predicted Functional Partners:
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
     
 0.931
PSEN1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
     
  0.800
ERBB2
Receptor protein-tyrosine kinase.
      
 0.721
NXF1
Uncharacterized protein.
      
 0.679
NFYC
Nuclear transcription factor Y subunit gamma.
      
 0.665
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
   0.646
RPS12
40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family.
    
 
 0.594
CTNNAL1
Catenin alpha like 1.
      
 0.593
ZNFX1
Zinc finger NFX1-type containing 1.
   
  
 0.589
RPL6
60S ribosomal protein L6; Belongs to the eukaryotic ribosomal protein eL6 family.
    
 
 0.526
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
Server load: low (18%) [HD]