Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SMAD2Mothers against decapentaplegic homolog. (467 aa)    
Predicted Functional Partners:
SMAD7
Mothers against decapentaplegic homolog.
    
0.995
SMAD1
Mothers against decapentaplegic homolog.
  
0.992
F7F0M1_MONDO
MH2 domain-containing protein.
  
0.992
SMAD4
Mothers against decapentaplegic homolog.
   
0.992
SMAD6
Mothers against decapentaplegic homolog.
    
0.989
SMAD5
Mothers against decapentaplegic homolog.
  
0.978
TGFBR1
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
   
 0.970
ZFYVE9
Zinc finger FYVE domain-containing protein.
   
 0.960
SMURF2
E3 ubiquitin-protein ligase.
    
 0.959
FOXH1
Forkhead box H1.
    
 0.945
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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