Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)    
Predicted Functional Partners:
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.999
ITGB3
Integrin beta; Belongs to the integrin beta chain family.
   
 0.997
ITGB5
Integrin beta; Belongs to the integrin beta chain family.
   
 0.994
ITGB8
Integrin beta; Belongs to the integrin beta chain family.
   
 0.990
ITGB2
Integrin beta.
   
 0.988
ITGA3
Integrin subunit alpha 3; Belongs to the integrin alpha chain family.
   
0.964
ITGB6
Integrin beta; Belongs to the integrin beta chain family.
   
 0.963
ITGBL1
Integrin subunit beta like 1.
   
 0.952
FLNB
Filamin B.
   
 0.934
FLNA
Filamin A.
   
 0.931
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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