Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HKDC1Hexokinase domain containing 1. (917 aa)    
Predicted Functional Partners:
HK1
Hexokinase 1.
   
  0.990
HK3
Hexokinase 3.
   
  0.971
GPI
Glucose-6-phosphate isomerase; Belongs to the GPI family.
   
 0.946
G6PD
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.
   
 
 0.943
H6PD
Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.
   
 
 0.942
TALDO1
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
   
 0.902
G6PC
Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.
     
 0.902
SORD
Sorbitol dehydrogenase.
   
 
 0.900
GALM
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
   
 
 0.898
GNPNAT1
Glucosamine 6-phosphate N-acetyltransferase.
   
 0.898
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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