STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (122 aa)    
Predicted Functional Partners:
WRN
WRN RecQ like helicase.
   
 0.991
LOC100024719
Ig-like domain-containing protein; Belongs to the MHC class I family.
   
0.977
MHC-I
Ig-like domain-containing protein; Belongs to the MHC class I family.
   
0.967
Modo-UA
Ig-like domain-containing protein; Belongs to the MHC class I family.
   
0.966
ENSMODP00000045298
MHC_I-like_Ag-recog domain-containing protein; Belongs to the MHC class I family.
   
 0.964
MODO-UB
Ig-like domain-containing protein; Belongs to the MHC class I family.
   
0.964
MODO-UG
Ig-like domain-containing protein.
   
 0.962
RPA1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
   
 0.943
RPA3
Replication protein A3.
   
 0.922
MODO-UK
Ig-like domain-containing protein; Belongs to the MHC class I family.
     
 0.914
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.