| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACLY | MMUT | ENSMODP00000018423 | ENSMODP00000023527 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Methylmalonyl-CoA mutase. | 0.881 |
| ACLY | PC | ENSMODP00000018423 | ENSMODP00000009736 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Pyruvate carboxylase. | 0.930 |
| ACLY | PCK1 | ENSMODP00000018423 | ENSMODP00000020614 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Phosphoenolpyruvate carboxykinase 1. | 0.897 |
| ACLY | PCK2 | ENSMODP00000018423 | ENSMODP00000052312 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Phosphoenolpyruvate carboxykinase 2, mitochondrial. | 0.887 |
| ACLY | SUCLA2 | ENSMODP00000018423 | ENSMODP00000014058 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.440 |
| ACLY | SUCLG1 | ENSMODP00000018423 | ENSMODP00000027982 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.929 |
| ACSF3 | MCEE | ENSMODP00000004721 | ENSMODP00000054750 | Acyl-CoA synthetase family member 3. | Methylmalonyl-CoA epimerase. | 0.902 |
| ACSF3 | MMAA | ENSMODP00000004721 | ENSMODP00000000606 | Acyl-CoA synthetase family member 3. | Metabolism of cobalamin associated A. | 0.601 |
| ACSF3 | MMUT | ENSMODP00000004721 | ENSMODP00000023527 | Acyl-CoA synthetase family member 3. | Methylmalonyl-CoA mutase. | 0.874 |
| MCEE | ACSF3 | ENSMODP00000054750 | ENSMODP00000004721 | Methylmalonyl-CoA epimerase. | Acyl-CoA synthetase family member 3. | 0.902 |
| MCEE | MMAA | ENSMODP00000054750 | ENSMODP00000000606 | Methylmalonyl-CoA epimerase. | Metabolism of cobalamin associated A. | 0.840 |
| MCEE | MMUT | ENSMODP00000054750 | ENSMODP00000023527 | Methylmalonyl-CoA epimerase. | Methylmalonyl-CoA mutase. | 0.972 |
| MCEE | SUCLA2 | ENSMODP00000054750 | ENSMODP00000014058 | Methylmalonyl-CoA epimerase. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.486 |
| MCEE | SUCLG1 | ENSMODP00000054750 | ENSMODP00000027982 | Methylmalonyl-CoA epimerase. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.571 |
| MMAA | ACSF3 | ENSMODP00000000606 | ENSMODP00000004721 | Metabolism of cobalamin associated A. | Acyl-CoA synthetase family member 3. | 0.601 |
| MMAA | MCEE | ENSMODP00000000606 | ENSMODP00000054750 | Metabolism of cobalamin associated A. | Methylmalonyl-CoA epimerase. | 0.840 |
| MMAA | MMUT | ENSMODP00000000606 | ENSMODP00000023527 | Metabolism of cobalamin associated A. | Methylmalonyl-CoA mutase. | 0.996 |
| MMUT | ACLY | ENSMODP00000023527 | ENSMODP00000018423 | Methylmalonyl-CoA mutase. | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.881 |
| MMUT | ACSF3 | ENSMODP00000023527 | ENSMODP00000004721 | Methylmalonyl-CoA mutase. | Acyl-CoA synthetase family member 3. | 0.874 |
| MMUT | MCEE | ENSMODP00000023527 | ENSMODP00000054750 | Methylmalonyl-CoA mutase. | Methylmalonyl-CoA epimerase. | 0.972 |
