STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLR2Toll like receptor 2; Belongs to the Toll-like receptor family. (785 aa)    
Predicted Functional Partners:
TLR4
Toll like receptor 4; Belongs to the Toll-like receptor family.
   
0.970
TIRAP
TIR domain-containing protein.
   
 0.953
TLR5
Toll like receptor 5; Belongs to the Toll-like receptor family.
   
0.947
TICAM1
TRIF-NTD domain-containing protein.
   
 0.934
TICAM2
TIR domain-containing protein.
   
 0.934
CD14
Uncharacterized protein.
   
0.934
NFKB1
Nuclear factor kappa B subunit 1.
   
 0.924
TOLLIP
CUE domain-containing protein.
    
 0.923
TLR9
TIR domain-containing protein.
   
 
0.921
RELA
RELA proto-oncogene, NF-kB subunit.
   
 0.920
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.