STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD244Ig-like domain-containing protein. (377 aa)    
Predicted Functional Partners:
SH2D1A
SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2.
   
 0.992
SH2D1B
SH2 domain-containing protein.
   
 0.951
LOC103101312
Ig-like domain-containing protein.
  
0.791
ENSMODP00000053081
Uncharacterized protein.
  
0.791
SLAMF8
SLAM family member 8.
   
0.774
ENSMODP00000055974
Ig-like domain-containing protein.
   
0.774
K7E5A3_MONDO
Ig-like domain-containing protein.
   
0.733
CD4
CD4.
   
  
 0.592
POLD2
DNA polymerase delta 2, accessory subunit.
    
 0.538
F6ZFC4_MONDO
SH2 domain-containing protein.
   
 0.531
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.