| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GY22_02455 | GY22_09900 | GY22_02455 | GY22_09900 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.947 |
| GY22_02455 | GY22_10490 | GY22_02455 | GY22_10490 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.863 |
| GY22_02455 | GY22_11630 | GY22_02455 | GY22_11630 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.881 |
| GY22_02455 | GY22_15690 | GY22_02455 | GY22_15690 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.781 |
| GY22_02455 | glyA | GY22_02455 | GY22_01245 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.878 |
| GY22_02455 | glyA-2 | GY22_02455 | GY22_10225 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.878 |
| GY22_02455 | hisF | GY22_02455 | GY22_03090 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.763 |
| GY22_02455 | metXA | GY22_02455 | GY22_08965 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.848 |
| GY22_02455 | trpA | GY22_02455 | GY22_03040 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.867 |
| GY22_02455 | trpC | GY22_02455 | GY22_03045 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional indole-3-glycerol phosphate synthase/tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpC family. | 0.883 |
| GY22_09900 | GY22_02455 | GY22_09900 | GY22_02455 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.947 |
| GY22_09900 | GY22_11630 | GY22_09900 | GY22_11630 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.549 |
| GY22_09900 | GY22_15690 | GY22_09900 | GY22_15690 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.939 |
| GY22_09900 | glyA | GY22_09900 | GY22_01245 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.661 |
| GY22_09900 | glyA-2 | GY22_09900 | GY22_10225 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.661 |
| GY22_10490 | GY22_02455 | GY22_10490 | GY22_02455 | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.863 |
| GY22_10490 | GY22_11630 | GY22_10490 | GY22_11630 | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Alanine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.893 |
| GY22_10490 | GY22_15690 | GY22_10490 | GY22_15690 | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.798 |
| GY22_10490 | glyA | GY22_10490 | GY22_01245 | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.816 |
| GY22_10490 | glyA-2 | GY22_10490 | GY22_10225 | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.943 |