Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GY22_11525Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)    
Predicted Functional Partners:
manB
Phosphomannomutase; Converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.986
GY22_09770
PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.978
GY22_02650
Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family.
  
 
 0.955
glmS
Glutamine amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.922
GY22_09195
Phosphomannomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.893
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
    
 0.887
GY22_08080
Ribokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.886
GY22_09765
1-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family.
    
 0.823
mtlD
Mannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.813
GY22_10570
Fructose 1,6-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.810
Your Current Organism:
Kocuria polaris
NCBI taxonomy Id: 136273
Other names: DSM 14382, JCM 12076, K. polaris, Kocuria polaris Reddy et al. 2003, MTCC 3702, NBRC 103063, strain CMS 76or
Server load: low (12%) [HD]