node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCA90883.1 | engD | LP2241_10016 | LP2241_10017 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Ribosome-binding ATPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.816 |
SCA90883.1 | pth | LP2241_10016 | LP2241_10018 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.553 |
argS | engD | LP2241_10331 | LP2241_10017 | Arginine--tRNA ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Ribosome-binding ATPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.677 |
argS | gltX | LP2241_10331 | LP2241_50214 | Arginine--tRNA ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.840 |
argS | guaA | LP2241_10331 | LP2241_30320 | Arginine--tRNA ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.992 |
argS | lepA | LP2241_10331 | LP2241_30380 | Arginine--tRNA ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | GTP-binding membrane protein or ribosomal elongation factor, GTPase; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.597 |
argS | metG | LP2241_10331 | LP2241_40045 | Arginine--tRNA ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.875 |
argS | pheT | LP2241_10331 | LP2241_50062 | Arginine--tRNA ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Phenylalanine--tRNA ligase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.754 |
argS | prfA | LP2241_10331 | LP2241_20324 | Arginine--tRNA ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Peptide chain release factor RF-1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.633 |
engD | SCA90883.1 | LP2241_10017 | LP2241_10016 | Ribosome-binding ATPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.816 |
engD | argS | LP2241_10017 | LP2241_10331 | Ribosome-binding ATPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | Arginine--tRNA ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.677 |
engD | gltX | LP2241_10017 | LP2241_50214 | Ribosome-binding ATPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.666 |
engD | guaA | LP2241_10017 | LP2241_30320 | Ribosome-binding ATPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.708 |
engD | lepA | LP2241_10017 | LP2241_30380 | Ribosome-binding ATPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | GTP-binding membrane protein or ribosomal elongation factor, GTPase; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.815 |
engD | metG | LP2241_10017 | LP2241_40045 | Ribosome-binding ATPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.743 |
engD | pheT | LP2241_10017 | LP2241_50062 | Ribosome-binding ATPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | Phenylalanine--tRNA ligase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.741 |
engD | prfA | LP2241_10017 | LP2241_20324 | Ribosome-binding ATPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | Peptide chain release factor RF-1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.755 |
engD | pth | LP2241_10017 | LP2241_10018 | Ribosome-binding ATPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.877 |
engD | topA | LP2241_10017 | LP2241_30337 | Ribosome-binding ATPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.762 |
gltX | argS | LP2241_50214 | LP2241_10331 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | Arginine--tRNA ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.840 |