node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gmk | ndk | LP2241_50171 | LP2241_30384 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.928 |
gmk | nrdE | LP2241_50171 | LP2241_30228 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase, major subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.914 |
gmk | nrdF | LP2241_50171 | LP2241_30229 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleotide diphosphate reductase, small subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.907 |
gmk | pyk | LP2241_50171 | LP2241_30265 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Pyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. | 0.933 |
gmk | relA | LP2241_50171 | LP2241_10089 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Bifunctional (p)ppGpp synthase/hydrolase RelA (Includes: GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.928 |
ndk | gmk | LP2241_30384 | LP2241_50171 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.928 |
ndk | nrdD | LP2241_30384 | LP2241_10145 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Anaerobic ribonucleoside-triphosphate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.914 |
ndk | nrdE | LP2241_30384 | LP2241_30228 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ribonucleoside-diphosphate reductase, major subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.916 |
ndk | nrdF | LP2241_30384 | LP2241_30229 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ribonucleotide diphosphate reductase, small subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.915 |
ndk | pyk | LP2241_30384 | LP2241_30265 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Pyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. | 0.911 |
ndk | relA | LP2241_30384 | LP2241_10089 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Bifunctional (p)ppGpp synthase/hydrolase RelA (Includes: GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.918 |
ndk | relP | LP2241_30384 | LP2241_20137 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | GTP pyrophosphokinase ((p)ppGpp synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.900 |
ndk | rplF | LP2241_30384 | LP2241_10240 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 50S ribosomal subunit protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.613 |
ndk | rplO | LP2241_30384 | LP2241_10244 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 50S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.807 |
ndk | rpsN | LP2241_30384 | LP2241_20322 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. | 0.997 |
nrdD | ndk | LP2241_10145 | LP2241_30384 | Anaerobic ribonucleoside-triphosphate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.914 |
nrdD | nrdF | LP2241_10145 | LP2241_30229 | Anaerobic ribonucleoside-triphosphate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Ribonucleotide diphosphate reductase, small subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.491 |
nrdD | pyk | LP2241_10145 | LP2241_30265 | Anaerobic ribonucleoside-triphosphate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Pyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. | 0.900 |
nrdD | relA | LP2241_10145 | LP2241_10089 | Anaerobic ribonucleoside-triphosphate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Bifunctional (p)ppGpp synthase/hydrolase RelA (Includes: GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.902 |
nrdD | relP | LP2241_10145 | LP2241_20137 | Anaerobic ribonucleoside-triphosphate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | GTP pyrophosphokinase ((p)ppGpp synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.900 |