STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argGArgininosuccinate synthase; Homologs of previously reported genes of unknown function;conserved hypothetical protein (containing DegV: EDD domain protein, DegV family) fragment 1; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (402 aa)    
Predicted Functional Partners:
argH
Argininosuccinate lyase (Arginosuccinase) (ASAL); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.999
pyrAB
Carbamoyl-phosphate synthase large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarB family.
 
 
 0.989
argF
Ornithine carbamoyltransferase 2, chain F; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
  
 
 0.969
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
  
 0.934
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.927
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
  
 0.918
pyrAA
Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family.
  
 
 0.911
asnA
Putative L-asparaginase AnsA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 
 0.910
pyrB
Aspartate carbamoyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
 
 0.909
SCA92468.1
Aspartate kinase III; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family.
 
 
 0.883
Your Current Organism:
Lactococcus piscium
NCBI taxonomy Id: 1364
Other names: ATCC 700018, CCUG 32207, CCUG 32732, CIP 104371, DSM 6634, JCM 11055, L. piscium, NCFB 2778, NCIMB 13196, strain HRIA 68
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