STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sorDSorbitol-6-phosphate 2-dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)    
Predicted Functional Partners:
srlA
Glucitol/sorbitol-specific enzyme IIC component of PTS; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
 
  0.993
srlE
Glucitol/sorbitol-specific enzyme IIB component of PTS; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.988
srlB
Putative PTS system, glucitol/sorbitol-specific IIA component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
 
 0.988
SCA91177.1
Glucitol operon activator protein; Function of homologous gene experimentally demonstrated in an other organism; regulator.
 
  
 0.951
SCA91176.1
Sorbitol operon transcription regulator; Function of strongly homologous gene; regulator.
 
  
 0.928
mtlD
Mannitol-1-phosphate 5-dehydrogenase, NAD(P)-binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.920
fbp
Fructose-1,6-bisphosphatase class 3; Function experimentally demonstrated in the studied genus; regulator;Transcriptional regulator, LacI family (Fragment 1).
  
 
  0.918
pfkA
6-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
   
 0.910
manA
Mannose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the mannose-6-phosphate isomerase type 1 family.
   
 
 0.906
scrK
Fructokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.905
Your Current Organism:
Lactococcus piscium
NCBI taxonomy Id: 1364
Other names: ATCC 700018, CCUG 32207, CCUG 32732, CIP 104371, DSM 6634, JCM 11055, L. piscium, NCFB 2778, NCIMB 13196, strain HRIA 68
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