STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioYBiotin synthase; Function of strongly homologous gene; enzyme. (189 aa)    
Predicted Functional Partners:
ecfT
Energy-coupling factor transporter transmembrane protein EcfT; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 0.978
ecfA-2
Energy-coupling factor transporter ATP-binding protein EcfA 2; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
 0.953
ecfA
Energy-coupling factor transporter ATP-binding protein EcfA 1; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
   
 0.944
bioY-2
Biotin transporter BioY2; Function experimentally demonstrated in the studied genus; transporter.
  
  
0.927
SCA91771.1
Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function.
  
 0.925
atoB
acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
  
    0.803
vraA
Putative long-chain-fatty-acid--CoA ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.797
birA
Biotin-protein ligase / Biotin operon repressor; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   
 0.742
SCA92600.1
Putative Bifunctional protein BirA (Includes: Biotin operon repressor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   
 0.729
thiT
Thiamine transporter ThiT; Function experimentally demonstrated in the studied genus; transporter.
   
  
 0.707
Your Current Organism:
Lactococcus piscium
NCBI taxonomy Id: 1364
Other names: ATCC 700018, CCUG 32207, CCUG 32732, CIP 104371, DSM 6634, JCM 11055, L. piscium, NCFB 2778, NCIMB 13196, strain HRIA 68
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