STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ponAPenicillin-binding protein 1A; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (674 aa)    
Predicted Functional Partners:
pbpX
Penicillin-binding protein 2x; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.982
penA
Penicillin-binding protein 2B; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.976
SCA92968.1
Putative D-alanyl-D-alanine carboxypeptidase DacA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase S11 family.
 
 
 0.931
SCA92907.1
Penicillin-binding protein 1B; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
0.927
SCA91082.1
Penicillin-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
0.926
recU
Holliday junction resolvase RecU; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
 
  
 0.852
rodA
Factor involved in extension of the lateral walls of the cell (cell wall shape-determining protein); Function of homologous gene experimentally demonstrated in an other organism; cell process; Belongs to the SEDS family.
 
 
 
 0.763
ftsW
Lipid II flippase FtsW; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the SEDS family.
 
 
 
 0.741
gpsB
Cell cycle protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
   
 
 0.677
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
   
 0.667
Your Current Organism:
Lactococcus piscium
NCBI taxonomy Id: 1364
Other names: ATCC 700018, CCUG 32207, CCUG 32732, CIP 104371, DSM 6634, JCM 11055, L. piscium, NCFB 2778, NCIMB 13196, strain HRIA 68
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